Kurzweil Overreaches

August 17th, 2010

No sooner do I disavow P.Z. Meyers than he turns up saying something important. He’s commenting on Priya Ganapati’s Gizmodo article about Ray Kurzweil’s assertion that

The design of the brain is in the genome. The human genome has three billion base pairs or six billion bits, which is about 800 million bytes before compression, he says. Eliminating redundancies and applying loss-less compression, that information can be compressed into about 50 million bytes, according to Kurzweil.

About half of that is the brain, which comes down to 25 million bytes, or a million lines of code.

Meyers responds

See that sentence I put in red up there? That’s his fundamental premise, and it is utterly false. Kurzweil knows nothing about how the brain works. It’s design is not encoded in the genome: what’s in the genome is a collection of molecular tools wrapped up in bits of conditional logic, the regulatory part of the genome, that makes cells responsive to interactions with a complex environment. The brain unfolds during development, by means of essential cell:cell interactions, of which we understand only a tiny fraction. The end result is a brain that is much, much more than simply the sum of the nucleotides that encode a few thousand proteins. He has to simulate all of development from his codebase in order to generate a brain simulator, and he isn’t even aware of the magnitude of that problem.

We cannot derive the brain from the protein sequences underlying it; the sequences are insufficient, as well, because the nature of their expression is dependent on the environment and the history of a few hundred billion cells, each plugging along interdependently. We haven’t even solved the sequence-to-protein-folding problem, which is an essential first step to executing Kurzweil’s clueless algorithm. And we have absolutely no way to calculate in principle all the possible interactions and functions of a single protein with the tens of thousands of other proteins in the cell!

Let me give you a few specific examples of just how wrong Kurzweil’s calculations are. Here are a few proteins that I plucked at random from the NIH database; all play a role in the human brain.

First up is RHEB (Ras Homolog Enriched in Brain). It’s a small protein, only 184 amino acids, which Kurzweil pretends can be reduced to about 12 bytes of code in his simulation. Here’s the short description.

MTOR (FRAP1; 601231) integrates protein translation with cellular nutrient status and growth signals through its participation in 2 biochemically and functionally distinct protein complexes, MTORC1 and MTORC2. MTORC1 is sensitive to rapamycin and signals downstream to activate protein translation, whereas MTORC2 is resistant to rapamycin and signals upstream to activate AKT (see 164730). The GTPase RHEB is a proximal activator of MTORC1 and translation initiation. It has the opposite effect on MTORC2, producing inhibition of the upstream AKT pathway (Mavrakis et al., 2008).

Got that? You can’t understand RHEB until you understand how it interacts with three other proteins, and how it fits into a complex regulatory pathway. Is that trivially deducible from the structure of the protein? No. It had to be worked out operationally, by doing experiments to modulate one protein and measure what happened to others. If you read deeper into the description, you discover that the overall effect of RHEB is to modulate cell proliferation in a tightly controlled quantitative way. You aren’t going to be able to simulate a whole brain until you know precisely and in complete detail exactly how this one protein works.

Dammit, and I thought Kurzweil was a schmot guy.

But let me poke a bit on Meyers, too: Simulating the brain down to the protein interactions isn’t going to work, either. The trick is going to be setting up a network of logic gates that can self-organize into a brain under the appropriate stimuli . And, no, we’re not going to understand how it works, either. [Yeah, that link goes to Meyers, too. He knows better.]

Then there’s this from the comments:

[Kurzweil thinks] he’ll be able to resurrect his dead father using DNA recovered from the latter’s grave plus records of his life. IOW, he believes in magic.

Even Jesus can't believe your idiocy.

via SF critic James Nicoll.

Traction

August 17th, 2010

Billy Beck, talking about tractors:

Ladies and gentlemen, this is about managing the immutable reality of mechanical systems. People can bullshit each other — and even themselves — over concepts in all sorts of ways. When concepts are forged in steel, that becomes impossible. You don’t get to bullshit your way around a 5/8″ bolt. You just don’t. When you’re dealing with a flywheel pilot bearing, no mental substitutions — whether from sloppiness or outright psychosis — will suffice: that bearing is only what it is, and your mind had better be right about everything about it.

Robert Pirsig once wrote a very ridiculous book, but he wrote it about a very serious subject.

There is great philosophy in machines.

Accompanied by some heart-warming shop photos.

[Hey, Billy! I've done a couple of head rebuilds, and my question is, where are you getting the gasket sets for this beast?]

This prompted Mike Soja:

I was standing in front of a green hooded idling number of about half the age of Beck’s specimen, while the man I was there to do business with slowly hand pumped diesel into the fuel neck from a large tank out behind his corn crib. Over the rumble, he pointed to the name plate at the prominent place on the nose and asked, “Ever see one of those before?” The plate said, “Deutz”, and I allowed that I hadn’t. He said it was a three cylinder, air cooled.

[He] remarked, “I’d like to buy a new one of these, but they don’t make them anymore.”

I asked, “Did they go out of business?”

“No. They just can’t make them. The government says they have to be water cooled, now.”

And that opened up whole new areas of conversation.

I’ve whacked out about half of that; see the whole thing for the flavor.

I’ve done volunteer teaching of fifth grade science labs. They stopped doing that;it was too damn much trouble, too messy, too loud.

I don’t know how much science got through, but if I managed to get across the faintest glimmer that the universe does what it does, and not what you think it ought to do, I succeeded.

Anybody who thinks economics doesn’t follow that same principle is advocating ruin, death, and chaos.

Ladies of State

August 14th, 2010


I understand the lady on the left is an actual princess, Spain’s Princess Letizia. Middle girl unidentified. Notice their shoulders and spines. Spines, you know, that part that goes straight up from those lovely, tight little….Ahem.

On the right, some no account American schlump who dresses about as well as I do, only a bit more garishly. And somebody needs to teach her how to walk.

Via Sondra K.

Red soles on charcoal heels. yowzers.

Can’t Find a Place to Land

August 14th, 2010

Storyville’s A Good Day For the Blues:

More Flintlocks, Less Crime

August 13th, 2010

Don B. Cates, writing at Cal Guns:

[The following is from an article that Carlyle Moody and I are writing on the theory that more guns in a society will cause more crime. This part of the article was written by Prof. Moody an economist at William & Mary College.]

If more guns cause murder, and more guns cause more murder, it would seem societies with no guns at all should be the safest possible states. There are few gun free societies in the world today. However, if we look back in history to the time before the invention of firearms, we can judge for ourselves whether those societies were tranquil and safe. Remarkably good homicide data is available for England, beginning in the 1200’s. Those data indicate a pre-gun homicide rate in England of roughly 20 per 100,000 [roughly four times greater than the U.S. today]

Firearms were introduced into England in the 1400’s and were in wide use by the 1500’s, coincident with a decline in the homicide rate to 15 per 100K. However these early guns were predominately of the matchlock design. This design featured a slow burning fuse held in a clamp at the end of a serpentine lever. When the trigger was pulled the clamp dropped down so that the end of the lit fuse touched the powder in the flash pan, firing the weapon. The design was simple and the weapons relatively inexpensive. The major problem with the design from the point of view of personal defense was that, because of the need for a lit fuse, the weapon could not be kept and carried loaded and primed for quick use against a sudden attack.

The first firearm that could be carried loaded and primed was the flintlock, introduced into England around 1630. In this design the fuse is replaced by a piece of flint. When the trigger is pulled the flint strikes a piece of steel producing a shower of sparks that ignite the powder in the flash pan. This technology persisted through the early 1800’s. While matchlocks were almost exclusively long guns, flintlock technology was readily adapted to produce handguns, which were particularly useful for self defense. The flintlock pistol was relatively inexpensive, could be comfortably carried, was ready for action in an instant, and did not require a great deal of physical strength or expertise to operate. The flintlock could be fired in an instant, making it the ideal self- defense weapon. Armed with a flintlock, the physically weak found themselves on an equal footing with the physically strong in a confrontation.

The introduction of the flintlock coincided with the largest decline in homicide in English history. The homicide rate plunged to 6 per 100K in the 1600’s. The English homicide rate continued to decline slowly and steadily until well into the 20th century. For example, in 1900 the homicide rate was 0.96 per 100K.

The last hundred years of English history tells the reverse story. The first modern gun law in England was the Pistols Act of 1903 which required Englishmen to purchase a permit in order to acquire a firearm. Since 1920, the English government’s policy has been ever more restrictive. The Firearms Control Act of 1920 imposed a true permit requirement to possess rifles as well as all types of pistols and empowered local authorities to determine if the applicant would be allowed to purchase arms. This permit requirement was administered progressively more stringently and was amended to increase restrictions over time in an attempt to reduce the civilian gun stock. The Prevention of Crime Act of 1953 and the Criminal Law Act of 1967 redefined the right to self defense more restrictively making any act of self defense potentially criminal. The Firearms Acts of 1968 and 1998 brought shotguns under strict regulation; the Firearm Act of 1997 effectively banned the private ownership of handguns and provided for the confiscation of all legally owned handguns.
According to the more guns more crime hypothesis, all this restriction of civilian guns should have resulted in England enjoying lower and lower rates of violent crime. Unfortunately, the facts reveal a pattern that is almost opposite. [as of 2000 England had twice the violent crime rate of the U.S.] and I are writing on the theory that more guns in a society will cause more crime. This part of the article was written by Prof. Moody an economist at William & Mary College.]

If more guns cause murder, and more guns cause more murder, it would seem societies with no guns at all should be the safest possible states. There are few gun free societies in the world today. However, if we look back in history to the time before the invention of firearms, we can judge for ourselves whether those societies were tranquil and safe. Remarkably good homicide data is available for England, beginning in the 1200’s. Those data indicate a pre-gun homicide rate in England of roughly 20 per 100,000 [roughly four times greater than the U.S. today]

Firearms were introduced into England in the 1400’s and were in wide use by the 1500’s, coincident with a decline in the homicide rate to 15 per 100K. However these early guns were predominately of the matchlock design. This design featured a slow burning fuse held in a clamp at the end of a serpentine lever. When the trigger was pulled the clamp dropped down so that the end of the lit fuse touched the powder in the flash pan, firing the weapon. The design was simple and the weapons relatively inexpensive. The major problem with the design from the point of view of personal defense was that, because of the need for a lit fuse, the weapon could not be kept and carried loaded and primed for quick use against a sudden attack.

The first firearm that could be carried loaded and primed was the flintlock, introduced into England around 1630. In this design the fuse is replaced by a piece of flint. When the trigger is pulled the flint strikes a piece of steel producing a shower of sparks that ignite the powder in the flash pan. This technology persisted through the early 1800’s. While matchlocks were almost exclusively long guns, flintlock technology was readily adapted to produce handguns, which were particularly useful for self defense. The flintlock pistol was relatively inexpensive, could be comfortably carried, was ready for action in an instant, and did not require a great deal of physical strength or expertise to operate. The flintlock could be fired in an instant, making it the ideal self- defense weapon. Armed with a flintlock, the physically weak found themselves on an equal footing with the physically strong in a confrontation.

The introduction of the flintlock coincided with the largest decline in homicide in English history. The homicide rate plunged to 6 per 100K in the 1600’s. The English homicide rate continued to decline slowly and steadily until well into the 20th century. For example, in 1900 the homicide rate was 0.96 per 100K.

The last hundred years of English history tells the reverse story. The first modern gun law in England was the Pistols Act of 1903 which required Englishmen to purchase a permit in order to acquire a firearm. Since 1920, the English government’s policy has been ever more restrictive. The Firearms Control Act of 1920 imposed a true permit requirement to possess rifles as well as all types of pistols and empowered local authorities to determine if the applicant would be allowed to purchase arms. This permit requirement was administered progressively more stringently and was amended to increase restrictions over time in an attempt to reduce the civilian gun stock. The Prevention of Crime Act of 1953 and the Criminal Law Act of 1967 redefined the right to self defense more restrictively making any act of self defense potentially criminal. The Firearms Acts of 1968 and 1998 brought shotguns under strict regulation; the Firearm Act of 1997 effectively banned the private ownership of handguns and provided for the confiscation of all legally owned handguns.
According to the more guns more crime hypothesis, all this restriction of civilian guns should have resulted in England enjoying lower and lower rates of violent crime. Unfortunately, the facts reveal a pattern that is almost opposite. [as of 2000 England had twice the violent crime rate of the U.S.]

[Emphasis in the original.]

Here it is again: the key tactic in any argument with a gun control advocate is to demand the citing of any instance where relaxing gun control laws has increased crime. And, I suspect, you can also do well by demanding the citing of any instance where imposing gun control on the general population has decreased crime. (The “on the general population” proviso is aimed at excepting closed, tightly controlled areas such as prisons. Presumably, most gun control advocates would not be willing to voluntarily live in a prison.)

===

Ack, I’ve lost the via.

Why I Can Not Mock

August 12th, 2010

I doubt that I will ever believe, as Elizabeth Scalia does, in the God she professes her faith to. I don’t think I can.

But as I have said before, there is a profound and beautiful core of truth to what the Anchoress believes, and I read her every day for the glimpses she vouchsafes us of that beauty.

In a former parish, there was a sister-liturgist who–eager to promote “sensitivity”–decided that the Gloria should be sung with the refrain “Glory to God in the Highest, and peace to God’s people on earth;” she was content to brutalize the ear, change a liturgical prayer that is not supposed to be changed, and disorient the people just a tad, in order that no one should be subjected to that troubling male pronoun, “His.”

I always thought it was a nonsensical point; why go to the trouble of training the people to avoid the “His” in that sung prayer, when it proceed to refer to God as “Heavenly King, Almighty God and Father,” and to Jesus as “only Son of the Father.” And of course, I got into a civil debate with her about it.

“You don’t understand,” she said kindly (because she was a very kind sister) “it’s important that we begin to think of God as having no gender at all, containing aspects of both mother and father, but not limited to our understanding as “Father.”

“Yes, mysticism if fine; I’m a fan,” I said. “But the prayer–which is liturgical and not subject for editing by you or me–makes enough male references throughout that it seems incongruous and silly, to enforce this clumsy and cold “Glory to God and peace to God’s people,” phrasing. It’s ick to my ear. And it puts God at a distance; it’s not intimate.”

To sister’s credit she remained kind but she did buckle down and let me know she wasn’t budging. “There are a lot of people in the world who have had bad fathers, they have bad memories, a lot of people find referring to God as “Father” to be distancing and hurtful. They cannot relate.”

“Well, sister, I happen to be one of those people who had a bad father and carries bad memories, and I like referencing God as Father; I happen to find great comfort and solace in having a Heavenly Father who more than fills the void left by my earthly one.”

She looked stunned. “You are the first person who has ever said that to me; that is not the usual perspective.”

“But don’t you think that’s a perspective worth promoting? Isn’t it a much better thing to tell people whose fathers have failed that they may be consoled by a Father who will never fail? Wouldn’t that be more positive, and ultimately more healing, than wrecking the liturgy to pander to neurotic sadness?”

Read it all.

This is why I continue to read Scalia, but have given up on, say, P.Z. Meyers. There is a profound and beautiful truth to what Meyers teaches as well, a truth arrived at by pathways easier for me to follow than the one illuminated by Scalia, a path that rejects the rigor of faith for a sharper, narrower rigor of another kind. But somehow, somewhere, Meyers has lost sight of that beauty, and has long ago ceased to teach his audience how to find it.

Instead, he wastes his time and talents mocking people like the Anchoress…and, yes, I see much to be mocked about them. I no longer care. Their various blindnesses and failings are trivial compared to their beauties and truths, which science cannot address, and may never be able to address — it is simply not the right tool to do so.

Not at all incidentally, I mind myself of Eric S. Raymond’s definition of “truth” , that truth is what makes the future less surprising. In what sense, you may then reasonably ask, do the Anchoress’ “truths” make the future less surprising? How may her words be unpacked as predictions?

I admit, I’m still struggling with how to express that. But in general, I think that people who think and believe as the Anchoress does are more likely to be, for lack of a better word, decent.

Gripe

August 12th, 2010

Why the hell do laundry detergent manufacturers put such heavy perfumes in their products?

My sheets, shirts, and pants reek.

Is there anybody who actually likes these stenches?

And another thing:

Front loading washers now require so-called “High Efficiency” detergents. We’ve got an LG, and it’s a wonder of quiet, and incredibly smart, but all our old detergent is useless. We’re strictly cautioned not to use it, because it will foam too much and clog the sensors or some such.

So I went out and bought a bottle of All Hypoallergenic, with no added dyes or perfumes — this simplification actually makes it cost more. I was sure to note that I had the HE version.

Then I noticed a larger bottle, similar label, but much cheaper per use. Got it home, started a load, and realized that, no, it wasn’t HE.

I’ll go back tomorrow and buy another bottle — but why, why, do I have to keep track of both these variables now? Why aren’t all detergents HE and stench free? Why can’t I get the stench free, HE version in the large economy size package?

Gah. I love capitalism, I do, but things like this are what mosquitoes are to evolution.

The Pantry Proof

August 10th, 2010

From Staghounds, a simple way to show collectivists that central planning will always lead to disaster.

It’s too short to excerpt, and Staghounds deserves the traffic for coming up with this.

Via Robb Allen at Sharp as a Marble, who does as good a job at summing up as possible: “You ever run out of sugar?”

Evocative, if not exactly illustrative, from Taking Hayek Seriously: 20 miles of empty lumber rail cars in Eastern Oregon.

[I'm posting Ransom's image here because he's having trouble getting the image to show up in-line.]

Sick At Heart

August 4th, 2010

Clayton Cramer is fighting the good fight against Righthaven, an operation that buys the copyrights on articles from the Las Vegas Review-Journal, then sues bloggers who have quoted any part of the article. I think they’re using the heinous Digital Millenium Copyright Act, which apparently allows suits for arbitrary amounts of money without first issuing a take-down notice.

Righthaven’s CEO, Steve Gibson, told Reason Magazine, “Media companies’ assets are very much their copyrights. These companies need to understand and appreciate that those assets have value more than merely the present advertising revenues.” [Information Liberation]

in other words, this isn’t about defending the copyright, which in most cases would involve a simple take-down notice. It’s a flat out shake-down.

Cramer’s pretty shaken about this. I’ve been reading him for years now, and I’ve never read anything like this from him:

When this matter is resolved, I’m retiring from all involvement with public policy, and doing my best to disappear. This system is so fundamentally corrupt, evil, and unwilling to reform itself that I no longer care to take any action to reform it or protect it. It needs to burn, and it needs to die. Why anyone would fight to defend a nation that is as corrupt and evil as this one leaves me utterly confused.

Gibson is doing real evil here. Cramer’s one of the good guys in my book, and and Gibson could well ruin him.

I’m going to miss him badly when he’s gone.

Why this story isn’t everywhere, I don’t understand. Cramer desperately needs help, and none of the people and organizations he’s helped are stepping up.

I’m looking forward to Gibson crashing and burning in court, if only someone with lawyers and money turns the tables on him.

More on Righthaven at Techdirt.

Techdirt also has this article on Righthaven’s self-justification.

Per informationliberation, it’s possible that Righthaven is specifically attacking right-leaning bloggers.

Oh, wait, except when, as Media Matters says, they’re specifically targeting left-wingers

Color From The Forties

August 3rd, 2010

Yes, it must have been really boring to live in a black and white world before the spectrum was invented in the fifties.

Except it wasn’t, of course. The Denver Post has some stunning color photos of American life in the early forties. These are gorgeous pictures, providing a breathtaking connection to the people of that time. (“People” like my parents.)

[aargh, I've lost my source for this. I'll post if I find it.]